CDS

Accession Number TCMCG025C00366
gbkey CDS
Protein Id XP_021644097.1
Location join(5699859..5699870,5699962..5700078,5700204..5700262,5700404..5700463,5700608..5700661,5700782..5700830,5700916..5700963,5701113..5701178,5701347..5701520)
Gene LOC110637982
GeneID 110637982
Organism Hevea brasiliensis

Protein

Length 212aa
Molecule type protein
Topology linear
Data_file_division PLN
dblink BioProject:PRJNA394253
db_source XM_021788405.1
Definition flap endonuclease 1-like [Hevea brasiliensis]

EGGNOG-MAPPER Annotation

COG_category L
Description Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic apyrimidinic (AP) site-terminated flap. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double- stranded DNA, and exhibits RNase H activity. Also involved in replication and repair of rDNA and in repairing mitochondrial DNA
KEGG_TC -
KEGG_Module -
KEGG_Reaction -
KEGG_rclass -
BRITE ko00000        [VIEW IN KEGG]
ko00001        [VIEW IN KEGG]
ko01000        [VIEW IN KEGG]
ko03032        [VIEW IN KEGG]
ko03400        [VIEW IN KEGG]
ko04147        [VIEW IN KEGG]
KEGG_ko ko:K04799        [VIEW IN KEGG]
EC -
KEGG_Pathway ko03030        [VIEW IN KEGG]
ko03410        [VIEW IN KEGG]
ko03450        [VIEW IN KEGG]
map03030        [VIEW IN KEGG]
map03410        [VIEW IN KEGG]
map03450        [VIEW IN KEGG]
GOs -

Sequence

CDS:  
ATGGGCATTAAGGGTTTAACGAAGCTGTTGGCGGATAATGCCCCGAAAGCTATGAAAGAGCAGAAATTTGAGAGCTACTTTGGCCGCAAGATTGCCATTGATGCCAGCATGAGCATCTACCAGTTCCTTATTGTAGTGGGAAGAATTGGAACTGAAATGCTTACTAATGAGGCTGGCGAAGTCACTAGCCATTTGCAAGGCATGTTTACTCGGACAATCAGGCTTCTTGAGGCTGGAATAAAGCCTGTTTATGTGTTTGATGGGCAGCCTCCAGACTTGAAAAAAGAAGAGCTGGCAAAGCGTTACTCAAGAAGGGCAGATGCTACTGAGGATTTGGCTCAAGCTGTGGAGACTGGCAACAAGGAAGACATTGAGAAATTCAGTAAGCGGACAGTGAAGGTAACAAAGCAGCACAATGAAGACTGCAAAAGACTTTTAAAACTCATGGGAGTACCTGTAATTGAGGCTCCTTCGGAGGCAGAGGCAGAGTGTGCTGCACTTTGCAAATCAGGAAAGGCATGTATTTTTCTGCTTTTTAATTTGGCTAGTTTTGGGTTCACTGTATGTTTGCATGGCATTTGGAATGGGTCCATTTTGTTTCTAATGCCTGAAGGGAATGGATTTATCCTTTTGTTTTAG
Protein:  
MGIKGLTKLLADNAPKAMKEQKFESYFGRKIAIDASMSIYQFLIVVGRIGTEMLTNEAGEVTSHLQGMFTRTIRLLEAGIKPVYVFDGQPPDLKKEELAKRYSRRADATEDLAQAVETGNKEDIEKFSKRTVKVTKQHNEDCKRLLKLMGVPVIEAPSEAEAECAALCKSGKACIFLLFNLASFGFTVCLHGIWNGSILFLMPEGNGFILLF